La Lupe 104.5 FM is a grupera radio station owned by Multimedios Radio. Its signal can be picked up live in Chihuahua at the frequency 104.5 FM and can also be listened to online through the official website of Multimedios Radio.

The station's programming includes a variety of entertainment shows, news broadcasts that present the most relevant local, national, and international news, as well as promotions and musical segments throughout its transmission. On La Lupe 104.5 FM, the hits of regional Mexican music are aired, covering both current major hits and classic past favorites, with a special emphasis on grupero and banda genres.